Peptide library · Performance & mood
Semax
ACTH(4-7) analog
Research stage7amino acids in this nasal peptide developed and used clinically in Russia
What it is
A short peptide based on a fragment of ACTH, linked in research to BDNF, a brain growth factor.
Why researchers are interested
- Russian stroke studies (181 patients combined) reported better neurological scores and mobility.
- Studied for decades in Russia for brain protection and focus.
Good to know
- Not FDA approved. An FDA panel voted 8 to 5 in July 2026 to allow compounding.
- No Western double blind trials yet.
Evidence level: 2 of 5
Sources
Bulletin of Rehabilitation Medicine 2018 (meta-analysis); McDermott, Jul 2026
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Educational content only. Not medical advice. Last reviewed 2026-10-17.